Leon Hotel And Hostel

Once you arrive in Prague, take the "C-Line" Subway to Terminal "Nadrazi Holesovice":
  from the metro platform up the escalator (exit "Plynarni ulice") and take the tram No. 5, 12 to "Ortenovo namesti" (1 stop), or you can go by walk, turn left to the crossroad with traffic lights and go straight along the street "Plynarni" to "Ortenovo namesti" (250 m)

From Ruzyne International Airport
  take the express bus Airport Express to "Nadrazi Holesovice", then follow instruction above

From the "Florenc" bus station
  take subway C (red line) 2 stops to "Nadrazi Holesovice", then follow instruction above

From Prague Main Railway Station "Hlavni nadrazi"
  take subway C (red line) 3 stops to "Nadrazi Holesovice", then follow instruction above

From the "Holesovice" railway station
  from the railway station (exit "Vrbenskeho ulice") walk through the local bus station and then upstairs along the overbridge "Vrbenskeho" to "Ortenovo namesti"

Perfect location
  good connection by public traffic service 24 hours a day
  5 minutes to the city centre by public transport or 20 minutes by walk
  you can reach Prague Castle, Charle's bridge, Old Town Square and all Prague historical monuments in a few minutes by subway or tram
  tram stop "Ortenovo namesti" near the hotel, subway station "Nadrazi Holesovice" only 250 m from the hotel
  express bus link Nadrazi Holesovice - Airport Ruzyne;
  train station "Nadrazi Holesovice" few minutes by walk